So I have been tying a lot of flies lately, and sad to say none of them were for me. Now that my tying list is finished I thought I'd try something new for me, and that being tying size 22 flies. I have tied #20's before and did somewhat ok with them. It all started with talking with a young lady at work who used to fish the San Juan River, which is a river known to have quality trout and possibly the pickiest trout on the planet. The river is heavily fished by people and because of that the fish have learned to pretty much eat only the smallest of flies. Midges seem to be the main meal for these fish and they seem to take flies just below the surface quite often.
I'm 55 years old, and my eyes are not what they used to be, but I have to say I am a little surprised at myself. The hardest part is the material always breaking. Peacock herl and hackle were the worst things to handle because they were so fragile. When it comes to small hooks I found that you have to be very gentle when applying the materials. Though the more I tied, the easier it became.
Now for the viewing.
Four Griffiths Gnats on a penny.
This fly is called Matt's Midge. It was first developed here in Colorado, but I don't know what year or where in Colorado it was first tied.
Here's three of Matt's Midges on a dime. I think I could have fit more on it.
This pattern really surprised me, a parachute midge. I didn't think I could do this, but after my first attempt I got into it and it almost became rhythmic. It was almost fun,
This is the first one, and it's not too shabby. 
I ended up tying a bunch of these little guys, and now I want to try tying the next size smaller. But why rush it? I'll keep with these until I get better and then I will try for smaller flies.
Do you use a flip down magnifier? Nigel raises a good point about standard hackling masking the hook point but trimming a vee out of the undercarriage helps here. Martin you are not alone in encouraging anglers to fish the midge and generally try smaller flies in the UK! One thing I would point out is that hook sizes vary wildly from one manufacturer and model to the next - Partridge in particular are renowned for this and almost all of their models are way over size. When fishing say caenis hatches in waters where larger fish can be encountered my patterns are mostly tied on a Kamasan/Drennan "Specialist' coarse fishing hook in a 22 which is the equivalent of the smallest Tiemco 26 and has a strong hold when in a fishes jaw.
They are fabulous Iasgair, works of art. I am in awe of your tying skills